sodium hyaluronate injection
1. Product name: Hyaluronic acid
2. CAS NO.: 9067-32-7
3. Molecular form: C14H22NNaO11
4. Specification as follows:
Physical Appearance | White powder or granules |
pH | 6.0-7.5 |
Transparency | ≥99.0% |
Loss on drying | ≤10.0% |
Limiting viscosity | 17.3~27.2 dl/g |
Protein | ≤0.05% |
Heavy metals | ≤20 ppm |
Glucuronic acid | ≥45.0% |
HA | ≥93.0% |
Bacteria counts | <10 cfu/g |
Mold & Yeast | <10 cfu/g |
Introduction:
Hyaluronic acid is connected alternately in Glycoside chain by D-Glucuronic acid and 2-Acetamido-2-deoxy-D-glucose, which is widely found in skin tissue. Its commercial form is exised in hyaluronic acid sodium salt form, sodium hyaluronate, as we call. The unique structure can bind and lock water molecular, showing its great ability in water retaining. Theoretically it can bind 100 times weight water of it’s own weight, 100ml/ g, so it is called the natural moisturizing factor (NMF).
High molecular weight sodium hyaluronate can form a thin permeable layer, which helps the skin lock water and protect the skin from hurting by bacteria, dust and ultraviolet rays.
Low molecular weight sodium hyaluronate can penetrate into corium, enlarge blood capillaries slightly to promote blood circulation, improve intermediary metabolism and stimulate the nourishment of skin cells, thus diminishing the wrinkles, boosting the skin elasticity and delaying the aging process.
Besides, sodium hyaluronate plays a part in hyperplasia of epidermic cell, cleaning of free radicals, preventing and recovering skin injuries.
Properties and applications:
Sodium hyaluronate is the perfect thicker and water retainer for personal care products. It has a strong compatibility and stability and could be widely applied to skin care and cosmetic products, such as cream, lotion, astringent, essence, facial cleanser, shower gel, shampoo, hair conditioner, mouse and lip sticker, etc. The recommended dosage is 0.05%-0.1%.
Sodium hyaluronate (Cosmetic Grade) |
Type | Molecular weight range | Function |
High molecular weight | 1800 kDa ~ 2000 kDa | Lubricating and film-forming, moisturizing, preventing skin damage, thickening and keeping emulsion stable |
2000 kDa ~ 2200 kDa |
2200 kDa ~ 2500 kDa |
Middle molecular weight | 1000 kDa ~ 1200 kDa |
1200 kDa ~ 1500 kDa |
1500 kDa ~ 1800 kDa |
Low molecular weight | 10 kDa ~ 100 kDa | Nourishing the skin, long-lasting moisturizing |
100 kDa ~ 500 kDa |
500 kDa ~ 1000 kDa |
Oligo | ≤10 kDa | Trans-dermal absorption, deep hydrating, anti-ageing, repairing skin damage |
Sodium Hyaluronate crosspolymer (Hyaluronic acid elastomer) | -- | Smooth and not sticky feeling; Forms a crosslinked network on the skin surface; Long-lasting moisturizing effect because of its good stability; Increases skin elasticity and reduces skin roughness. |
Substantive Sodium Hyaluronate | -- | High Substantivity, It can be used in rinse-off products. As a conditioning moisturizer It helps to reduce the inflammation to the skin caused by surfactants present in formulas and feeling smooth. |
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